Eliminating barriers to pharmacogenomics implementation
For health systems, payers, labs, and providers
Access a team of regulatory, clinical, and laboratory experts to unlock the benefits of pharmacogenomics (PGx) for your organization.
Making PGx accessible
The benefits of PGx are well documented, but effectively achieving the cost savings and improved patient outcomes of a PGx program requires specific expertise. End to End Pharmacogenomics (E2E PGx) brings together clinical, regulatory, and laboratory experts that can help bridge the gap between wanting a PGx program and implementing one.
Services
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Due diligence review of laboratory pharmacogenomics tests and reports to assist with test selection
Assistance developing and improving clinical decision support tools
Program development consulting including process creation, documentation, MTM note structure, and team training and education
Program consulting including program evaluation, gap analysis, and quality improvement recommendations
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Protocol development support
Regulatory assistance with IRB submissions and/or FDA regulatory assessments and submissions (e.g., IND or IDE)
Assistance with assessing and meeting CLIA, CAP, NYSDOH, and/or FDA standards
Assistance with white paper and poster creation
PGx experts for webinar or in-person presentations
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Due diligence review of laboratory pharmacogenomics tests and reports to assist with test selection
Program development consulting including process documentation, and team training and education
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Educational tools for physicians, pharmacists, laboratories, and more
Tools for practitioners to educate their patients
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Continuing education
Webinars and in-person PGx presentations
About Us
We launched E2E PGx with the aim of advancing pharmacogenomics across the healthcare ecosystem.
Our Experts
Bronwyn Ramey, PhD
Dr. Bronwyn Ramey has nearly 20 years of experience in pharmacogenomics, successfully launching numerous labs from concept to operations. She has managed all facets of testing, quality systems, product development, and regulatory compliance for start-ups and large healthcare systems. She is committed to service and volunteers with STRIPE, PharmVar, CPIC, PGRN, and the European Molecular Genetics Quality Network. As a director, she has repeatedly achieved exceptional turnaround times, vanishing failure rates, and laboratory excellence by always seeking to "fix what hurts." Dr. Ramey has driven the development of in-house LIMS products, LDT validations on various platforms, and pharmacogenomic interpretation algorithms, including novel haplotypers. She is also well-versed in CAP, New York State CLEP, and FDA.
Wrenda Teeple, PharmD, BCPS
Dr. Wrenda Teeple is a leader in pharmacogenomics and regulatory strategy with over a decade of experience. As President of Arbit Consulting, LLC, she develops innovative solutions to advance precision medicine and improve patient care. Co-chairing the STRIPE Study Designs Task Force with the FDA, she has driven the standardization of pharmacogenetic testing, earning the STRIPE Double Helix Award for Excellence. A passionate educator, Dr. Teeple lectures on pharmacogenomics and regulatory affairs at institutions like the University of Minnesota. Her work at OneOme and Regions Hospital reflects her commitment to reducing healthcare disparities and enhancing patient outcomes. Dr. Teeple holds a Doctor of Pharmacy degree from the University of Minnesota, is board-certified in pharmacotherapy, and is skilled in FDA regulatory frameworks and quality systems.
Jennifer Nelson, PharmD
Dr. Jennifer Nelson is a pharmacogenomics pharmacist and regulatory affairs specialist with experience in all stages of clinical implementation. She has specialized training in clinical implementation of pharmacogenomics through her PGY2 in pharmacogenomics at Children’s Minnesota and certificate training through the Mayo Clinic. Dr. Nelson has created and presented numerous educational materials and scientific posters to a wide range of audiences. Her early research work with underrepresented populations highlights her passion for improving health disparities using pharmacogenomics. Dr. Nelson has continued to be a leader and educator in the field of pharmacogenomics and strives to improve patient outcomes by equitable implementation of clinical pharmacogenomics.
Our Mission
PGx has the potential to revolutionize prescribing and significantly improve health outcomes; however, disparities in adoption and accessibility stand in the way.
At E2E PGx, our mission is to help eliminate disparities by supporting best practice PGx deployment across healthcare institutions, payers, pharmacies, and labs. We believe that consistent, thoughtful practice is the pathway to realizing the benefits of PGx for every population.
Join us in creating a future where PGx is accessible to everyone.
UProoting The Disparity in PGx
PGx testing holds immense potential to improve treatment outcomes, but disparities persist in its adoption and application. Underrepresented populations often face barriers such as:
Limited access to testing due to cost or geographic constraints
Underrepresentation in PGx research, leading to gaps in genetic databases
Lack of education about PGx benefits among both patients and providers
Bridging the Inequity Gap
We are dedicated to advancing health equity in pharmacogenomics through 4 core strategies:
1
Affordable Solutions
Collaborating with healthcare systems and policymakers to reduce the cost burden of PGx testing, ensuring affordability for all.
2
Diverse Genetic Research
Partnering with global research initiatives to include underrepresented populations in PGx studies, creating more inclusive data.
3
Provider and Community Education
Offering training programs and resources to demystify PGx for clinicians and communities alike, fostering informed decision-making.
4
Advocating for Policy Change
Working with stakeholders to integrate PGx testing into public health frameworks and expand coverage by insurers.
Contact Us
Take the first step toward building a PGx program that improves outcomes and reduces costs. We’re looking forward to helping you make your PGx vision a reality.
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